General Information of the Compound
Compound ID
CP0445556
Compound Name
4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate
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Synonyms
JZL 195
JZL-195
JZL195
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Structure
Formula
C24H23N3O5
Molecular Weight
433.464
Canonical SMILES
[O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3cccc(Oc4ccccc4)c3)CC2)cc1
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InChI
InChI=1S/C24H23N3O5/c28-24(32-22-11-9-20(10-12-22)27(29)30)26-15-13-25(14-16-26)18-19-5-4-8-23(17-19)31-21-6-2-1-3-7-21/h1-12,17H,13-16,18H2
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InChIKey
QNYRAEKLMNDRFY-UHFFFAOYSA-N
Physicochemical Property
logP
4.7037
Rotatable Bonds
6
Heavy Atom Count
32
Polar Areas
85.15
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46232606
SID: 99289601
ChEMBL ID
CHEMBL606201
Clinical Information about the Compound
Drug 1 ( JZL195 )
Drug Name JZL195