General Information of the Compound
Compound ID
CP0443189
Compound Name
N-[1-(4-chlorophenyl)-3-(dimethylamino)propyl]-3-(4-methoxyphenyl)propanamide
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Structure
Formula
C21H27ClN2O2
Molecular Weight
374.912
Canonical SMILES
COc1ccc(CCC(=O)NC(CCN(C)C)c2ccc(Cl)cc2)cc1
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InChI
InChI=1S/C21H27ClN2O2/c1-24(2)15-14-20(17-7-9-18(22)10-8-17)23-21(25)13-6-16-4-11-19(26-3)12-5-16/h4-5,7-12,20H,6,13-15H2,1-3H3,(H,23,25)
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InChIKey
BMMSRFZZLSBZRR-UHFFFAOYSA-N
Physicochemical Property
logP
4.0904
Rotatable Bonds
9
Heavy Atom Count
26
Polar Areas
41.57
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 15983449
SID: 24775219
ChEMBL ID
CHEMBL228461
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 2951.21 nM
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