General Information of the Compound
| Compound ID |
CP0443137
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
7-[5-chloro-4-(3,5-dimethylpyridin-2-yl)pyridin-2-yl]-N-(3,4-difluorophenyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazine-2-carboxamide
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C25H21ClF2N6O
|
||||||||||||||||||
| Molecular Weight |
494.933
|
||||||||||||||||||
| Canonical SMILES |
Cc1cnc(c(C)c1)-c1cc(ncc1Cl)N1CCn2cc(nc2C1)C(=O)Nc1ccc(F)c(F)c1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C25H21ClF2N6O/c1-14-7-15(2)24(30-10-14)17-9-22(29-11-18(17)26)34-6-5-33-12-21(32-23(33)13-34)25(35)31-16-3-4-19(27)20(28)8-16/h3-4,7-12H,5-6,13H2,1-2H3,(H,31,35)
Show/Hide
|
||||||||||||||||||
| InChIKey |
LPFHUFINDXZPRT-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound