General Information of the Compound
Compound ID
CP0440665
Compound Name
[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(methoxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl] [hydroxy(naphthalen-2-yloxy)phosphoryl] hydrogen phosphate
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Structure
Formula
C20H24N3O15P3
Molecular Weight
639.34
Canonical SMILES
CO\N=c1\ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)Oc3ccc4ccccc4c3)[C@@H](O)[C@H]2O)c(=O)[nH]1
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InChI
InChI=1S/C20H24N3O15P3/c1-33-22-16-8-9-23(20(26)21-16)19-18(25)17(24)15(35-19)11-34-39(27,28)37-41(31,32)38-40(29,30)36-14-7-6-12-4-2-3-5-13(12)10-14/h2-10,15,17-19,24-25H,11H2,1H3,(H,27,28)(H,29,30)(H,31,32)(H,21,22,26)/t15-,17-,18-,19-/m1/s1
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InChIKey
ONBWUVFXPXDHHZ-NXWXRZEISA-N
Physicochemical Property
logP
0.8409
Rotatable Bonds
11
Heavy Atom Count
41
Polar Areas
257.89
Hydrogen Bond Donor Count
6
Hydrogen Bond Acceptor Count
14
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 90666799
ChEMBL ID
CHEMBL3220055
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04714, P2Y purinoceptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
EC50 = 2900 nM
   TI
   LI
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   TS
Protein ID: PT02796, P2Y purinoceptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
EC50 = 731 nM
   TI
   LI
   LO
   TS