General Information of the Compound
Compound ID
CP0438113
Compound Name
(5S,6R,10R,11S)-5-benzyl-10-heptyl-6-hydroxy-4,11-dimethyl-1,9-dioxa-4-azacyclododecane-3,8,12-trione
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Structure
Formula
C25H37NO6
Molecular Weight
447.572
Canonical SMILES
CCCCCCC[C@H]1OC(=O)C[C@@H](O)[C@H](Cc2ccccc2)N(C)C(=O)COC(=O)[C@H]1C
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InChI
InChI=1S/C25H37NO6/c1-4-5-6-7-11-14-22-18(2)25(30)31-17-23(28)26(3)20(21(27)16-24(29)32-22)15-19-12-9-8-10-13-19/h8-10,12-13,18,20-22,27H,4-7,11,14-17H2,1-3H3/t18-,20-,21+,22+/m0/s1
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InChIKey
BLMHSWGWEUOGCI-VXSCBNMQSA-N
Physicochemical Property
logP
3.2723
Rotatable Bonds
8
Heavy Atom Count
32
Polar Areas
93.14
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44285907
ChEMBL ID
CHEMBL290049
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01546, ATP-dependent translocase ABCB1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001059 P388/VMDRC.04 Mus musculus (Mouse)  2
1
IC50 = 5800 nM
   TI
   LI
   LO
   TS
2
IC50 = 22500 nM
   TI
   LI
   LO
   TS