General Information of the Compound
Compound ID
CP0437739
Compound Name
N-[4-[2-[4-(1-anilino-2-methyl-1-oxopropan-2-yl)oxyphenyl]ethoxy]phenyl]benzamide
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Structure
Formula
C31H30N2O4
Molecular Weight
494.591
Canonical SMILES
CC(C)(Oc1ccc(CCOc2ccc(NC(=O)c3ccccc3)cc2)cc1)C(=O)Nc1ccccc1
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InChI
InChI=1S/C31H30N2O4/c1-31(2,30(35)33-25-11-7-4-8-12-25)37-28-17-13-23(14-18-28)21-22-36-27-19-15-26(16-20-27)32-29(34)24-9-5-3-6-10-24/h3-20H,21-22H2,1-2H3,(H,32,34)(H,33,35)
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InChIKey
BMLOPJYGLSCLGH-UHFFFAOYSA-N
Physicochemical Property
logP
6.3565
Rotatable Bonds
10
Heavy Atom Count
37
Polar Areas
76.66
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 156020214
ChEMBL ID
CHEMBL4648827
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00910, Peroxisome proliferator-activated receptor alpha
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 12300 nM
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