General Information of the Compound
Compound ID
CP0437696
Compound Name
2-(furan-2-yl)-N7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-5,7-diamine
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Structure
Formula
C24H30N8O3
Molecular Weight
478.557
Canonical SMILES
COCCOc1ccc(cc1)N1CCN(CCNc2cc3nc(nn3c(N)n2)-c2ccco2)CC1
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InChI
InChI=1S/C24H30N8O3/c1-33-15-16-34-19-6-4-18(5-7-19)31-12-10-30(11-13-31)9-8-26-21-17-22-28-23(20-3-2-14-35-20)29-32(22)24(25)27-21/h2-7,14,17,26H,8-13,15-16H2,1H3,(H2,25,27)
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InChIKey
KQDOPPPFRYWNIG-UHFFFAOYSA-N
Physicochemical Property
logP
2.2258
Rotatable Bonds
10
Heavy Atom Count
35
Polar Areas
119.21
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
11
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44571585
ChEMBL ID
CHEMBL480749
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 9.5 nM
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