General Information of the Compound
Compound ID
CP0432924
Compound Name
(E)-4-[4-[[2,4-dimethyl-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]phenyl]-N-(1-hydroxy-2-methylpropan-2-yl)-2,2-dimethylbut-3-enamide
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Structure
Formula
C31H43NO7
Molecular Weight
541.685
Canonical SMILES
Cc1cc(C)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
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InChI
InChI=1S/C31H43NO7/c1-18-13-19(2)23(28-27(37)26(36)25(35)24(16-33)39-28)15-22(18)14-21-9-7-20(8-10-21)11-12-30(3,4)29(38)32-31(5,6)17-34/h7-13,15,24-28,33-37H,14,16-17H2,1-6H3,(H,32,38)/b12-11+/t24-,25-,26+,27-,28+/m1/s1
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InChIKey
AWSZFCZAYVENEU-LZMGQMCUSA-N
Physicochemical Property
logP
2.33564
Rotatable Bonds
9
Heavy Atom Count
39
Polar Areas
139.48
Hydrogen Bond Donor Count
6
Hydrogen Bond Acceptor Count
7
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 155521866
ChEMBL ID
CHEMBL4450704
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03804, Sodium/glucose cotransporter 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
Protein ID: PT02415, Sodium/glucose cotransporter 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS