General Information of the Compound
Compound ID
CP0430567
Compound Name
CHEMBL169885
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Formula
C26H31NO5
Molecular Weight
437.536
Canonical SMILES
Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)OCCC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)c1
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InChI
InChI=1S/C26H31NO5/c28-21-2-4-23(29)19(10-21)15-27-20-1-3-24(30)22(11-20)25(31)32-6-5-26-12-16-7-17(13-26)9-18(8-16)14-26/h1-4,10-11,16-18,27-30H,5-9,12-15H2/t16-,17+,18-,26?
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InChIKey
UKUPIEIGJLWQAX-QXRPDJHGSA-N
Physicochemical Property
logP
5.1788
Rotatable Bonds
7
Heavy Atom Count
32
Polar Areas
99.02
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
6
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL169885
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00922, Epidermal growth factor receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000520 39ER22 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 1250 nM
   TI
   LI
   LO
   TS
2
IC50 >> 5000 nM
   TI
   LI
   LO
   TS