General Information of the Compound
| Compound ID |
CP0426002
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| Compound Name |
2-[[4-hydroxy-2-oxo-1-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-5,7-dihydrofuro[3,4-b]pyridine-3-carbonyl]amino]acetic acid
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| Structure |
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| Formula |
C16H13F3N4O6
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| Molecular Weight |
414.296
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| Canonical SMILES |
OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cnc(cn2)C(F)(F)F)c1=O
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| InChI |
InChI=1S/C16H13F3N4O6/c17-16(18,19)10-2-20-7(1-21-10)4-23-9-6-29-5-8(9)13(26)12(15(23)28)14(27)22-3-11(24)25/h1-2,26H,3-6H2,(H,22,27)(H,24,25)
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| InChIKey |
JDLGXHQNBSGCLL-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02612, Egl nine homolog 1
Protein ID: PT01988, Prolyl hydroxylase EGLN2
Protein ID: PT02885, Prolyl hydroxylase EGLN3