General Information of the Compound
Compound ID
CP0425758
Compound Name
2-(furan-2-yl)-7-(3-(4-(3-phenylpropoxy)phenyl)propyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
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Structure
Formula
C27H25N7O2
Molecular Weight
479.544
Canonical SMILES
Nc1nc2n(CCCc3ccc(OCCc4ccccc4)cc3)ncc2c2nc(nn12)-c1ccco1
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InChI
InChI=1S/C27H25N7O2/c28-27-31-25-22(26-30-24(32-34(26)27)23-9-5-16-36-23)18-29-33(25)15-4-8-20-10-12-21(13-11-20)35-17-14-19-6-2-1-3-7-19/h1-3,5-7,9-13,16,18H,4,8,14-15,17H2,(H2,28,31)
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InChIKey
MVXHTCZBUPZAOJ-UHFFFAOYSA-N
Physicochemical Property
logP
4.5705
Rotatable Bonds
9
Heavy Atom Count
36
Polar Areas
109.29
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
9
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 52945120
ChEMBL ID
CHEMBL1258525
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 78.9 nM
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