General Information of the Compound
Compound ID
CP0423030
Compound Name
2-Methyl-c-5-[4-(5-methyl-2-phenyloxazol-4-ylmethoxy)benzyl]-1,3-dioxane-s-2-carboxylic acid
    Show/Hide
Formula
C24H25NO6
Molecular Weight
423.465
Canonical SMILES
Cc1oc(nc1COc1ccc(C[C@H]2CO[C@](C)(OC2)C(O)=O)cc1)-c1ccccc1
    Show/Hide
InChI
InChI=1S/C24H25NO6/c1-16-21(25-22(31-16)19-6-4-3-5-7-19)15-28-20-10-8-17(9-11-20)12-18-13-29-24(2,23(26)27)30-14-18/h3-11,18H,12-15H2,1-2H3,(H,26,27)/t18-,24+
    Show/Hide
InChIKey
PDHHMAZLDSSIHQ-OWWJJEGGSA-N
Physicochemical Property
logP
4.23532
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
91.02
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
ChEMBL ID
CHEMBL512084
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00910, Peroxisome proliferator-activated receptor alpha
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 1.09 nM
   TI
   LI
   LO
   TS
Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 96 nM
   TI
   LI
   LO
   TS