General Information of the Compound
Compound ID
CP0416652
Compound Name
tert-butyl N-[2-[2-[(E)-2-(4-tert-butylphenyl)ethenyl]-3H-benzimidazol-5-yl]phenyl]carbamate
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Structure
Formula
C30H33N3O2
Molecular Weight
467.613
Canonical SMILES
CC(C)(C)OC(=O)Nc1ccccc1-c1ccc2[nH]c(\C=C\c3ccc(cc3)C(C)(C)C)nc2c1
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InChI
InChI=1S/C30H33N3O2/c1-29(2,3)22-15-11-20(12-16-22)13-18-27-31-25-17-14-21(19-26(25)32-27)23-9-7-8-10-24(23)33-28(34)35-30(4,5)6/h7-19H,1-6H3,(H,31,32)(H,33,34)/b18-13+
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InChIKey
NWCRPUDZGTWWAP-QGOAFFKASA-N
Physicochemical Property
logP
8.0448
Rotatable Bonds
4
Heavy Atom Count
35
Polar Areas
67.01
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 24758929
SID: 49662756
ChEMBL ID
CHEMBL3426343
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02183, Transient receptor potential cation channel subfamily V member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS