General Information of the Compound
Compound ID
CP0407118
Compound Name
N-[2-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl]pyridine-3-carboxamide
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Structure
Formula
C20H14F3N3O2
Molecular Weight
385.345
Canonical SMILES
FC(F)(F)c1cccc(NC(=O)c2ccccc2NC(=O)c2cccnc2)c1
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InChI
InChI=1S/C20H14F3N3O2/c21-20(22,23)14-6-3-7-15(11-14)25-19(28)16-8-1-2-9-17(16)26-18(27)13-5-4-10-24-12-13/h1-12H,(H,25,28)(H,26,27)
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InChIKey
CABLZLANVVFNQB-UHFFFAOYSA-N
Physicochemical Property
logP
4.605
Rotatable Bonds
4
Heavy Atom Count
28
Polar Areas
71.09
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 56593303
ChEMBL ID
CHEMBL3718178
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05999, Relaxin receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
AC50 = 5930 nM
   TI
   LI
   LO
   TS
2
EC50 = 5930 nM
   TI
   LI
   LO
   TS