General Information of the Compound
Compound ID
CP0404315
Compound Name
(3S,6S,9S,12R,15S,18R,21R,24R,30S,33S)-33-(cyclohexylmethyl)-30-ethyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
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Structure
Formula
C62H111N11O11
Molecular Weight
1186.636
Canonical SMILES
CC[C@@H]1NC(=O)[C@H](CC2CCCCC2)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](CC(C)C)N(C)C(=O)[C@H](NC(=O)[C@@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C
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InChI
InChI=1S/C62H111N11O11/c1-23-44-58(80)67(16)34-50(74)68(17)45(29-35(2)3)56(78)66-51(39(10)11)61(83)69(18)46(30-36(4)5)54(76)63-41(14)53(75)64-42(15)57(79)71(20)48(31-37(6)7)59(81)72(21)49(32-38(8)9)60(82)73(22)52(40(12)13)62(84)70(19)47(55(77)65-44)33-43-27-25-24-26-28-43/h35-49,51-52H,23-34H2,1-22H3,(H,63,76)(H,64,75)(H,65,77)(H,66,78)/t41-,42+,44-,45+,46+,47-,48-,49-,51+,52-/m0/s1
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InChIKey
OPTOHMIKNVREEU-NWNXXRGOSA-N
Physicochemical Property
logP
4.2762
Rotatable Bonds
13
Heavy Atom Count
84
Polar Areas
258.57
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
11
Complexity
84

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 73347184
ChEMBL ID
CHEMBL2372476
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01546, ATP-dependent translocase ABCB1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000108 CCRF-CEM Homo sapiens (Human)  1
1
IC50 = 8100 nM
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Protein ID: PT02015, fMet-Leu-Phe receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  1
1
IC50 = 6330 nM
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