General Information of the Compound
Compound ID
CP0403620
Compound Name
2-(4-chloro-2-fluorophenoxy)-2-(4-chlorophenyl)acetic acid
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Structure
Formula
C14H9Cl2FO3
Molecular Weight
315.127
Canonical SMILES
OC(=O)C(Oc1ccc(Cl)cc1F)c1ccc(Cl)cc1
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InChI
InChI=1S/C14H9Cl2FO3/c15-9-3-1-8(2-4-9)13(14(18)19)20-12-6-5-10(16)7-11(12)17/h1-7,13H,(H,18,19)
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InChIKey
PSMGAHLRUIFDMM-UHFFFAOYSA-N
Physicochemical Property
logP
4.3372
Rotatable Bonds
4
Heavy Atom Count
20
Polar Areas
46.53
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
20

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 57397473
ChEMBL ID
CHEMBL1956371
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00910, Peroxisome proliferator-activated receptor alpha
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 10300 nM
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Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 16400 nM
   TI
   LI
   LO
   TS