General Information of the Compound
Compound ID
CP0402196
Compound Name
1,8-Dihydroxy-10-(3-phenyl-propionyl)-10H-anthracen-9-one
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Structure
Formula
C23H18O4
Molecular Weight
358.393
Canonical SMILES
Oc1cccc2C(C(=O)CCc3ccccc3)c3cccc(O)c3C(=O)c12
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InChI
InChI=1S/C23H18O4/c24-17-10-4-8-15-20(19(26)13-12-14-6-2-1-3-7-14)16-9-5-11-18(25)22(16)23(27)21(15)17/h1-11,20,24-25H,12-13H2
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InChIKey
LMVOEPVFPJXPBF-UHFFFAOYSA-N
Physicochemical Property
logP
3.976
Rotatable Bonds
4
Heavy Atom Count
27
Polar Areas
74.6
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10361032
SID: 15374243
ChEMBL ID
CHEMBL130302
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00205, 5-lipoxygenase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000831 PMNL Homo sapiens (Human)  1
1
IC50 = 500 nM
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