General Information of the Compound
Compound ID
CP0396671
Compound Name
5-O-[[1-[2-[2-[2-[2-[2-[2-[4-[[5-ethoxycarbonyl-2,6-dimethyl-4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-1,4-dihydropyridine-3-carbonyl]oxymethyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl] 3-O-ethyl 2,6-dimethyl-4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylate
    Show/Hide
Structure
Formula
C60H72N10O15
Molecular Weight
1173.291
Canonical SMILES
CCOC(=O)C1=C(C)NC(C)=C(C1c1c(C)onc1-c1ccccc1)C(=O)OCc1cn(CCOCCOCCOCCOCCOCCn2cc(COC(=O)C3=C(C)NC(C)=C(C3c3c(C)onc3-c3ccccc3)C(=O)OCC)nn2)nn1
    Show/Hide
InChI
InChI=1S/C60H72N10O15/c1-9-80-57(71)47-37(3)61-39(5)49(53(47)51-41(7)84-65-55(51)43-17-13-11-14-18-43)59(73)82-35-45-33-69(67-63-45)21-23-75-25-27-77-29-31-79-32-30-78-28-26-76-24-22-70-34-46(64-68-70)36-83-60(74)50-40(6)62-38(4)48(58(72)81-10-2)54(50)52-42(8)85-66-56(52)44-19-15-12-16-20-44/h11-20,33-34,53-54,61-62H,9-10,21-32,35-36H2,1-8H3
    Show/Hide
InChIKey
BWOFJGLIPMRXRZ-UHFFFAOYSA-N
Physicochemical Property
logP
6.66224
Rotatable Bonds
32
Heavy Atom Count
85
Polar Areas
288.89
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
25
Complexity
85

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 137645885
ChEMBL ID
CHEMBL4084565
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01546, ATP-dependent translocase ABCB1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000034 Caco-2 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS