General Information of the Compound
Compound ID
CP0394854
Compound Name
1-[(3E)-3-(5-methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)propyl]piperidine
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Structure
Formula
C19H27NO
Molecular Weight
285.431
Canonical SMILES
COc1cccc2\C(CCCc12)=C\CCN1CCCCC1
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InChI
InChI=1S/C19H27NO/c1-21-19-12-6-10-17-16(8-5-11-18(17)19)9-7-15-20-13-3-2-4-14-20/h6,9-10,12H,2-5,7-8,11,13-15H2,1H3/b16-9+
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InChIKey
OQZQEGAAANHHRE-CXUHLZMHSA-N
Physicochemical Property
logP
4.2909
Rotatable Bonds
4
Heavy Atom Count
21
Polar Areas
12.47
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Complexity
21

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44451346
ChEMBL ID
CHEMBL264424
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01546, ATP-dependent translocase ABCB1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000034 Caco-2 Homo sapiens (Human)  1
1
EC50 = 8200 nM
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