General Information of the Compound
Compound ID
CP0394424
Compound Name
4-ethyl-4-hydroxy-N-(4-methoxy-7-morpholin-4-yl-1,3-benzothiazol-2-yl)-1-methylcyclohexane-1-carboxamide
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Structure
Formula
C22H31N3O4S
Molecular Weight
433.574
Canonical SMILES
CCC1(O)CCC(C)(CC1)C(=O)Nc1nc2c(OC)ccc(N3CCOCC3)c2s1
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InChI
InChI=1S/C22H31N3O4S/c1-4-22(27)9-7-21(2,8-10-22)19(26)24-20-23-17-16(28-3)6-5-15(18(17)30-20)25-11-13-29-14-12-25/h5-6,27H,4,7-14H2,1-3H3,(H,23,24,26)
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InChIKey
IORLBYTXGBSKRB-UHFFFAOYSA-N
Physicochemical Property
logP
3.8014
Rotatable Bonds
5
Heavy Atom Count
30
Polar Areas
83.92
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137635665
ChEMBL ID
CHEMBL4061522
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 25 nM
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   LI
   LO
   TS