General Information of the Compound
Compound ID
CP0387604
Compound Name
2-[(2R,3S,4R,5R)-5-(2,4-dioxo-5-thiophen-2-ylpyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]ethylphosphonic acid
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Structure
Formula
C14H17N2O8PS
Molecular Weight
404.337
Canonical SMILES
O[C@@H]1[C@@H](CCP(O)(O)=O)O[C@H]([C@@H]1O)n1cc(-c2cccs2)c(=O)[nH]c1=O
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InChI
InChI=1S/C14H17N2O8PS/c17-10-8(3-4-25(21,22)23)24-13(11(10)18)16-6-7(9-2-1-5-26-9)12(19)15-14(16)20/h1-2,5-6,8,10-11,13,17-18H,3-4H2,(H,15,19,20)(H2,21,22,23)/t8-,10-,11-,13-/m1/s1
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InChIKey
ROOVZVHCVONLJJ-UORFTKCHSA-N
Physicochemical Property
logP
-0.5479
Rotatable Bonds
5
Heavy Atom Count
26
Polar Areas
162.08
Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
8
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 57384080
SID: 136913903
ChEMBL ID
CHEMBL1957444
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04714, P2Y purinoceptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
EC50 = 500 nM
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