General Information of the Compound
| Compound ID |
CP0386245
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| Compound Name |
(1R,2R)-N-[4-[6-(dimethylamino)pyridin-2-yl]-3-(2-methylindazol-5-yl)-1,2-thiazol-5-yl]-2-methylcyclopropane-1-carboxamide
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| Structure |
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| Formula |
C23H24N6OS
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| Molecular Weight |
432.553
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| Canonical SMILES |
C[C@@H]1C[C@H]1C(=O)Nc1snc(c1-c1cccc(n1)N(C)C)-c1ccc2nn(C)cc2c1
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| InChI |
InChI=1S/C23H24N6OS/c1-13-10-16(13)22(30)25-23-20(18-6-5-7-19(24-18)28(2)3)21(27-31-23)14-8-9-17-15(11-14)12-29(4)26-17/h5-9,11-13,16H,10H2,1-4H3,(H,25,30)/t13-,16-/m1/s1
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| InChIKey |
WWWXSZYKLGLJCL-CZUORRHYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01994, Metabotropic glutamate receptor 1
Protein ID: PT00854, Metabotropic glutamate receptor 5