General Information of the Compound
| Compound ID |
CP0372296
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| Compound Name |
5-(azetidin-1-yl)-N2-(2,6-dichlorophenyl)-N7-(4-(trifluoromethyl)phenyl)thiazolo[5,4-d]pyrimidine-2,7-diamine
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| Structure |
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| Formula |
C21H15Cl2F3N6S
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| Molecular Weight |
511.36
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| Canonical SMILES |
FC(F)(F)c1ccc(Nc2nc(nc3sc(Nc4c(Cl)cccc4Cl)nc23)N2CCC2)cc1
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| InChI |
InChI=1S/C21H15Cl2F3N6S/c22-13-3-1-4-14(23)15(13)28-20-29-16-17(27-12-7-5-11(6-8-12)21(24,25)26)30-19(31-18(16)33-20)32-9-2-10-32/h1,3-8H,2,9-10H2,(H,28,29)(H,27,30,31)
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| InChIKey |
RFNPVIJJFNCWFA-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01914, Transient receptor potential cation channel subfamily V member 1
Protein ID: PT02183, Transient receptor potential cation channel subfamily V member 1