General Information of the Compound
Compound ID
CP0367348
Compound Name
2-[3-(3,4-Dichloro-phenoxy)-propyl]-5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
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Structure
Formula
C21H22Cl2N2O
Molecular Weight
389.326
Canonical SMILES
Cn1c2CCN(CCCOc3ccc(Cl)c(Cl)c3)Cc2c2ccccc12
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InChI
InChI=1S/C21H22Cl2N2O/c1-24-20-6-3-2-5-16(20)17-14-25(11-9-21(17)24)10-4-12-26-15-7-8-18(22)19(23)13-15/h2-3,5-8,13H,4,9-12,14H2,1H3
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InChIKey
MVJJASJBZKVQAK-UHFFFAOYSA-N
Physicochemical Property
logP
5.3123
Rotatable Bonds
5
Heavy Atom Count
26
Polar Areas
17.4
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10872812
SID: 15917815
ChEMBL ID
CHEMBL126897
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01492, 5-hydroxytryptamine receptor 2A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
Ki = 195 nM
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   LI
   LO
   TS