General Information of the Compound
Compound ID
CP0357634
Compound Name
(S)-2,6-Diamino-hexanoic acid (2-{6-[3-((S)-2,6-diamino-hexanoylamino)-propionylamino]-9,10-dioxo-9,10-dihydro-anthracen-2-ylcarbamoyl}-ethyl)-amide
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Structure
Formula
C32H44N8O6
Molecular Weight
636.754
Canonical SMILES
NCCCC[C@H](N)C(=O)NCCC(=O)Nc1ccc2C(=O)c3cc(NC(=O)CCNC(=O)[C@@H](N)CCCCN)ccc3C(=O)c2c1
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InChI
InChI=1S/C32H44N8O6/c33-13-3-1-5-25(35)31(45)37-15-11-27(41)39-19-7-9-21-23(17-19)29(43)22-10-8-20(18-24(22)30(21)44)40-28(42)12-16-38-32(46)26(36)6-2-4-14-34/h7-10,17-18,25-26H,1-6,11-16,33-36H2,(H,37,45)(H,38,46)(H,39,41)(H,40,42)/t25-,26-/m0/s1
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InChIKey
LLWCZKJYRRFFEA-UIOOFZCWSA-N
Physicochemical Property
logP
0.2642
Rotatable Bonds
18
Heavy Atom Count
46
Polar Areas
254.62
Hydrogen Bond Donor Count
8
Hydrogen Bond Acceptor Count
10
Complexity
46

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 25107498
SID: 56479892
ChEMBL ID
CHEMBL449879
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01466, Telomerase reverse transcriptase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000428 JR8 Homo sapiens (Human)  1
1
EC50 = 800 nM
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Cell Viability or Cytotoxicity Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 100000 nM
   TI
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   TS