General Information of the Compound
| Compound ID |
CP0349925
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| Compound Name |
N-(5-chloro-2-fluorophenyl)-7-methoxy-6-[1-(2-methoxyethyl)piperidin-4-yl]oxyquinazolin-4-amine
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| Structure |
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| Formula |
C23H26ClFN4O3
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| Molecular Weight |
460.937
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| Canonical SMILES |
COCCN1CCC(CC1)Oc1cc2c(Nc3cc(Cl)ccc3F)ncnc2cc1OC
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| InChI |
InChI=1S/C23H26ClFN4O3/c1-30-10-9-29-7-5-16(6-8-29)32-22-12-17-19(13-21(22)31-2)26-14-27-23(17)28-20-11-15(24)3-4-18(20)25/h3-4,11-14,16H,5-10H2,1-2H3,(H,26,27,28)
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| InChIKey |
CXHUEJLZRIDMGV-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound