General Information of the Compound
Compound ID
CP0334186
Compound Name
3,3'-difluoro-4'-(pyridin-2-ylaminomethyl)-biphenyl-2-carboxylic acid methyl ester
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Structure
Formula
C20H16F2N2O2
Molecular Weight
354.356
Canonical SMILES
COC(=O)c1c(F)cccc1-c1ccc(CNc2ccccn2)c(F)c1
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InChI
InChI=1S/C20H16F2N2O2/c1-26-20(25)19-15(5-4-6-16(19)21)13-8-9-14(17(22)11-13)12-24-18-7-2-3-10-23-18/h2-11H,12H2,1H3,(H,23,24)
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InChIKey
QFANIHXSNQVFLE-UHFFFAOYSA-N
Physicochemical Property
logP
4.4255
Rotatable Bonds
5
Heavy Atom Count
26
Polar Areas
51.22
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44411297
ChEMBL ID
CHEMBL208538