General Information of the Compound
Compound ID
CP0332112
Compound Name
N,N-diethyl-4-[piperidin-4-ylidene(pyridin-2-yl)methyl]benzamide
    Show/Hide
Structure
Formula
C22H27N3O
Molecular Weight
349.478
Canonical SMILES
CCN(CC)C(=O)c1ccc(cc1)C(=C1CCNCC1)c1ccccn1
    Show/Hide
InChI
InChI=1S/C22H27N3O/c1-3-25(4-2)22(26)19-10-8-17(9-11-19)21(18-12-15-23-16-13-18)20-7-5-6-14-24-20/h5-11,14,23H,3-4,12-13,15-16H2,1-2H3
    Show/Hide
InChIKey
BQLCODXUHBHTCW-UHFFFAOYSA-N
Physicochemical Property
logP
3.7489
Rotatable Bonds
5
Heavy Atom Count
26
Polar Areas
45.23
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 57391826
ChEMBL ID
CHEMBL1946619
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01200, Delta-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 2.4 nM
   TI
   LI
   LO
   TS
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS