General Information of the Compound
Compound ID
CP0328212
Compound Name
(2,6-Dimethyl-phenyl)-[4-(4-methanesulfonyl-benzyl)-4'-methyl-[1,4']bipiperidinyl-1'-yl]-methanone
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Structure
Formula
C28H38N2O3S
Molecular Weight
482.69
Canonical SMILES
Cc1cccc(C)c1C(=O)N1CCC(C)(CC1)N1CCC(Cc2ccc(cc2)S(C)(=O)=O)CC1
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InChI
InChI=1S/C28H38N2O3S/c1-21-6-5-7-22(2)26(21)27(31)29-18-14-28(3,15-19-29)30-16-12-24(13-17-30)20-23-8-10-25(11-9-23)34(4,32)33/h5-11,24H,12-20H2,1-4H3
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InChIKey
JYDQSSJQXSQYRG-UHFFFAOYSA-N
Physicochemical Property
logP
4.65634
Rotatable Bonds
5
Heavy Atom Count
34
Polar Areas
57.69
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 511307
SID: 16163114
ChEMBL ID
CHEMBL106982
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05087, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
Ki = 33 nM
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