General Information of the Compound
| Compound ID |
CP0327714
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| Compound Name |
5-(2,4-dichlorophenyl)-N-(4-piperazin-1-ylphenyl)furan-2-carboxamide
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| Structure |
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| Formula |
C21H19Cl2N3O2
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| Molecular Weight |
416.308
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| Canonical SMILES |
Clc1ccc(-c2ccc(o2)C(=O)Nc2ccc(cc2)N2CCNCC2)c(Cl)c1
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| InChI |
InChI=1S/C21H19Cl2N3O2/c22-14-1-6-17(18(23)13-14)19-7-8-20(28-19)21(27)25-15-2-4-16(5-3-15)26-11-9-24-10-12-26/h1-8,13,24H,9-12H2,(H,25,27)
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| InChIKey |
GJQZQVRIRSQPIP-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01231, MAP kinase-activated protein kinase 2
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000229 | SW1353 | Homo sapiens (Human) | 1 |
| 1 |
CC50 = 8100 nM
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