General Information of the Compound
Compound ID
CP0280987
Compound Name
N-(3,4-dihydro-2H-chromen-2-ylmethyl)-N'-(1,4,5,6-tetrahydropyrimidin-2-yl)pentane-1,5-diamine
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Structure
Formula
C19H30N4O
Molecular Weight
330.476
Canonical SMILES
C(CCNCC1CCc2ccccc2O1)CCNC1=NCCCN1
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InChI
InChI=1S/C19H30N4O/c1(5-12-21-19-22-13-6-14-23-19)4-11-20-15-17-10-9-16-7-2-3-8-18(16)24-17/h2-3,7-8,17,20H,1,4-6,9-15H2,(H2,21,22,23)
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InChIKey
FGWYYRTVGNYTGY-UHFFFAOYSA-N
Physicochemical Property
logP
2.079
Rotatable Bonds
8
Heavy Atom Count
24
Polar Areas
57.68
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
5
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44323162
ChEMBL ID
CHEMBL88784
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00819, 5-hydroxytryptamine receptor 1A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000803 HA7 Homo sapiens (Human)  1
1
IC50 = 5.012 nM
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