General Information of the Compound
| Compound ID |
CP0276783
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
N-(3-chloro-6-methoxypyridin-2-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-propan-2-yloxyquinazolin-4-amine
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C24H31ClN6O3
|
||||||||||||||||||
| Molecular Weight |
487.004
|
||||||||||||||||||
| Canonical SMILES |
COc1ccc(Cl)c(Nc2ncnc3cc(OCCN4CCN(C)CC4)cc(OC(C)C)c23)n1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C24H31ClN6O3/c1-16(2)34-20-14-17(33-12-11-31-9-7-30(3)8-10-31)13-19-22(20)24(27-15-26-19)29-23-18(25)5-6-21(28-23)32-4/h5-6,13-16H,7-12H2,1-4H3,(H,26,27,28,29)
Show/Hide
|
||||||||||||||||||
| InChIKey |
PKVYBWGFOWKFHZ-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound