General Information of the Compound
| Compound ID |
CP0272476
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
Teniposide
Show/Hide
|
||||||||||||||||||
| Synonyms |
4'-Demethyl-epipodophyllotoxin-beta-D-thenylidene-glucoside
4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin 9-(4,6-O-2-thenylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin thenylidene glucoside
4'-Demethylepipodophyllotoxin-beta-D-thenylidine glucoside
4'-Dimethyl-9-(4,6-O-2-thenyid)-epipodophyllotoxin
4-Demethylepipodophyllotoxin-.beta.-D-thenylideneglucoside
Demethyl Epipodophyllotoxin Thenylidine Glucoside
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-2-thenylidene-beta-D-glucopyranoside)
PTG
Teniposide
Teniposide (USAN/INN)
Teniposide [USAN:BAN:INN]
Teniposido
Teniposido [INN-Spanish]
Teniposidum
Teniposidum [INN-Latin]
VM 26
VM-26
VM-26 (TN)
Vee M-26
Veham-Sandoz
Vehem
Vumon
Vumon (TN)
Vumon, VM-26, Vehem, NSC 122819, Teniposide
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C32H32O13S
|
||||||||||||||||||
| Molecular Weight |
656.662
|
||||||||||||||||||
| Canonical SMILES |
COc1cc(cc(OC)c1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@H](O[C@H]3[C@H](O)[C@H]2O)c2cccs2)c2cc3OCOc3cc12
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C32H32O13S/c1-37-19-6-13(7-20(38-2)25(19)33)23-14-8-17-18(42-12-41-17)9-15(14)28(16-10-39-30(36)24(16)23)44-32-27(35)26(34)29-21(43-32)11-40-31(45-29)22-4-3-5-46-22/h3-9,16,21,23-24,26-29,31-35H,10-12H2,1-2H3/t16-,21+,23+,24-,26+,27+,28+,29+,31+,32-/m0/s1
Show/Hide
|
||||||||||||||||||
| InChIKey |
NRUKOCRGYNPUPR-QBPJDGROSA-N
|
||||||||||||||||||
| CAS |
29767-20-2
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
| DrugBank ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03222, ATP-binding cassette sub-family C member 3
Protein ID: PT05334, ATP-binding cassette sub-family C member 4
Clinical Information about the Compound