General Information of the Compound
Compound ID
CP0268031
Compound Name
(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionic acid
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Structure
Formula
C12H16N2O4
Molecular Weight
252.27
Canonical SMILES
C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O
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InChI
InChI=1S/C12H16N2O4/c1-7(12(17)18)14-11(16)10(13)6-8-2-4-9(15)5-3-8/h2-5,7,10,15H,6,13H2,1H3,(H,14,16)(H,17,18)/t7-,10-/m0/s1
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InChIKey
NLKUJNGEGZDXGO-XVKPBYJWSA-N
Physicochemical Property
logP
-0.1487
Rotatable Bonds
5
Heavy Atom Count
18
Polar Areas
112.65
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
4
Complexity
18

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 5496455
SID: 14770605
ChEMBL ID
CHEMBL316103
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02822, Solute carrier family 15 member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000031 MDCK Canis lupus familiaris (Dog)  1
1
EC50 = 100000 nM
   TI
   LI
   LO
   TS
CL000034 Caco-2 Homo sapiens (Human)  1
1
Ki = 90000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 90000 nM