General Information of the Compound
Compound ID
CP0257367
Compound Name
1-(5-oxo-6-pyridin-4-ylpyrido[2,3-b][1,5]benzoxazepin-9-yl)-3-phenylurea
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Formula
C24H17N5O3
Molecular Weight
423.432
Canonical SMILES
O=C(Nc1ccccc1)Nc1ccc2N(c3ccncc3)C(=O)c3cccnc3Oc2c1
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InChI
InChI=1S/C24H17N5O3/c30-23-19-7-4-12-26-22(19)32-21-15-17(28-24(31)27-16-5-2-1-3-6-16)8-9-20(21)29(23)18-10-13-25-14-11-18/h1-15H,(H2,27,28,31)
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InChIKey
FKBZVMKCOKELFC-UHFFFAOYSA-N
Physicochemical Property
logP
5.2048
Rotatable Bonds
3
Heavy Atom Count
32
Polar Areas
96.45
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4788035