General Information of the Compound
Compound ID
CP0257194
Compound Name
7-N-[4-(2-methoxyethoxy)phenyl]-6-methyl-5-N-[(3S)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine
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Structure
Formula
C21H28N6O2
Molecular Weight
396.495
Canonical SMILES
COCCOc1ccc(Nc2c(C)c(N[C@H]3CCCNC3)nc3ccnn23)cc1
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InChI
InChI=1S/C21H28N6O2/c1-15-20(24-17-4-3-10-22-14-17)26-19-9-11-23-27(19)21(15)25-16-5-7-18(8-6-16)29-13-12-28-2/h5-9,11,17,22,25H,3-4,10,12-14H2,1-2H3,(H,24,26)/t17-/m0/s1
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InChIKey
JPEZXBCEWYKFBS-KRWDZBQOSA-N
Physicochemical Property
logP
2.97042
Rotatable Bonds
8
Heavy Atom Count
29
Polar Areas
84.74
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
8
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 60200737
SID: 144218544
ChEMBL ID
CHEMBL2163616