General Information of the Compound
| Compound ID |
CP0255814
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
[3-(3,4-dichlorophenyl)imidazo[4,5-b]pyridin-2-yl]-(3,3-difluoroazetidin-1-yl)methanone
Show/Hide
|
||||||||||||||||||
| Formula |
C16H10Cl2F2N4O
|
||||||||||||||||||
| Molecular Weight |
383.185
|
||||||||||||||||||
| Canonical SMILES |
FC1(F)CN(C1)C(=O)c1nc2cccnc2n1-c1ccc(Cl)c(Cl)c1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C16H10Cl2F2N4O/c17-10-4-3-9(6-11(10)18)24-13-12(2-1-5-21-13)22-14(24)15(25)23-7-16(19,20)8-23/h1-6H,7-8H2
Show/Hide
|
||||||||||||||||||
| InChIKey |
KQDYNRPFUNNOAV-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01305, 3',5'-cyclic-AMP phosphodiesterase 4B
Protein ID: PT01538, 3',5'-cyclic-AMP phosphodiesterase 4D