General Information of the Compound
| Compound ID |
CP0240487
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| Compound Name |
[(3R)-3-[[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]methyl]morpholin-4-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
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| Structure |
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| Formula |
C23H22FN7O2
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| Molecular Weight |
447.474
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| Canonical SMILES |
Cc1ccc(c(c1)C(=O)N1CCOC[C@H]1Cn1ccc(n1)-c1ccc(F)cn1)-n1nccn1
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| InChI |
InChI=1S/C23H22FN7O2/c1-16-2-5-22(31-26-7-8-27-31)19(12-16)23(32)30-10-11-33-15-18(30)14-29-9-6-21(28-29)20-4-3-17(24)13-25-20/h2-9,12-13,18H,10-11,14-15H2,1H3/t18-/m1/s1
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| InChIKey |
OKROKECXNXWALA-GOSISDBHSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01132, Orexin receptor type 2
Protein ID: PT02001, Orexin/Hypocretin receptor type 1