General Information of the Compound
Compound ID
CP0233777
Compound Name
9-(3-(dimethylamino)propyl)-2-(4-ethoxy-3-(trifluoromethyl)phenyl)-9H-purine-6-carbonitrile
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Structure
Formula
C20H21F3N6O
Molecular Weight
418.423
Canonical SMILES
CCOc1ccc(cc1C(F)(F)F)-c1nc(C#N)c2ncn(CCCN(C)C)c2n1
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InChI
InChI=1S/C20H21F3N6O/c1-4-30-16-7-6-13(10-14(16)20(21,22)23)18-26-15(11-24)17-19(27-18)29(12-25-17)9-5-8-28(2)3/h6-7,10,12H,4-5,8-9H2,1-3H3
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InChIKey
UHFLVCRUHSLCAK-UHFFFAOYSA-N
Physicochemical Property
logP
3.73418
Rotatable Bonds
7
Heavy Atom Count
30
Polar Areas
79.86
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46911635
SID: 99372638
ChEMBL ID
CHEMBL1209534