General Information of the Compound
Compound ID
CP0217596
Compound Name
N-(1,2-benzoxazol-3-yl)-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1,4-diazepane-1-carboxamide
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Structure
Formula
C21H20N6O2S
Molecular Weight
420.498
Canonical SMILES
O=C(Nc1noc2ccccc12)N1CCCN(CC1)c1nc(ns1)-c1ccccc1
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InChI
InChI=1S/C21H20N6O2S/c28-20(22-19-16-9-4-5-10-17(16)29-24-19)26-11-6-12-27(14-13-26)21-23-18(25-30-21)15-7-2-1-3-8-15/h1-5,7-10H,6,11-14H2,(H,22,24,28)
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InChIKey
MQDPEPZXWZYTOC-UHFFFAOYSA-N
Physicochemical Property
logP
4.0905
Rotatable Bonds
3
Heavy Atom Count
30
Polar Areas
87.39
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71508673
SID: 163496424
ChEMBL ID
CHEMBL2326186
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01099, Fatty-acid amide hydrolase 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 > 1000 nM
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