General Information of the Compound
Compound ID
CP0210709
Compound Name
2-Furan-2-yl-N*5*-[3-(4-phenyl-piperazin-1-yl)-propyl]-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
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Structure
Formula
C21H25N9O
Molecular Weight
419.493
Canonical SMILES
Nc1nc(NCCCN2CCN(CC2)c2ccccc2)nc2nc(nn12)-c1ccco1
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InChI
InChI=1S/C21H25N9O/c22-19-25-20(26-21-24-18(27-30(19)21)17-8-4-15-31-17)23-9-5-10-28-11-13-29(14-12-28)16-6-2-1-3-7-16/h1-4,6-8,15H,5,9-14H2,(H3,22,23,24,25,26,27)
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InChIKey
ATLUGIZVRICDDK-UHFFFAOYSA-N
Physicochemical Property
logP
1.9857
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
113.64
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
10
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44394688
ChEMBL ID
CHEMBL187810
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 1.3 nM
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