General Information of the Compound
Compound ID
CP0206583
Compound Name
US8530648, 78
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Structure
Formula
C27H28N6O2
Molecular Weight
468.561
Canonical SMILES
Cc1noc(n1)-c1ccccc1CN1CCCC2(CCN(CC2)c2cnc3ccccc3n2)C1=O
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InChI
InChI=1S/C27H28N6O2/c1-19-29-25(35-31-19)21-8-3-2-7-20(21)18-33-14-6-11-27(26(33)34)12-15-32(16-13-27)24-17-28-22-9-4-5-10-23(22)30-24/h2-5,7-10,17H,6,11-16,18H2,1H3
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InChIKey
ORQIXYIDXFFJOU-UHFFFAOYSA-N
Physicochemical Property
logP
4.39742
Rotatable Bonds
4
Heavy Atom Count
35
Polar Areas
88.25
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 53259467
SID: 124400787
ChEMBL ID
CHEMBL2413514