General Information of the Compound
Compound ID
CP0189579
Compound Name
US8765972, 127
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Structure
Formula
C21H28FN3O2
Molecular Weight
373.472
Canonical SMILES
CC1N(C2CCN(CC2)C2CCCCC2)C(=O)c2c1cc(F)cc2C(N)=O
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InChI
InChI=1S/C21H28FN3O2/c1-13-17-11-14(22)12-18(20(23)26)19(17)21(27)25(13)16-7-9-24(10-8-16)15-5-3-2-4-6-15/h11-13,15-16H,2-10H2,1H3,(H2,23,26)
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InChIKey
JMSHIEXDPIOMCA-UHFFFAOYSA-N
Physicochemical Property
logP
3.2385
Rotatable Bonds
3
Heavy Atom Count
27
Polar Areas
66.64
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49871952
SID: 104546898
ChEMBL ID
CHEMBL3701692