General Information of the Compound
Compound ID
CP0189235
Compound Name
CHEBI:87690
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Synonyms
Latixa
(-)-Ranolazine
142387-99-3
95635-55-5
C24H33N3O4
CHEBI:87690
CVT 303
CVT-303
DSSTox_CID_25196
DSSTox_GSID_45196
DSSTox_RID_80743
KEG-1295
Latixa
N-(2,6-dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide
N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide
NCGC00015897-02
RAN D
RANOLAZINE
RS-43285
RS-43285-003
Ran4
Ranexa
Ranexa (TN)
Ranexa, Ranolazine
Ranolazine
Ranolazine (Ranexa)
Ranolazine (USAN/INN)
Ranolazine 2HCl
Ranolazine dihydrochloride
Ranolazine extended-release
Ranolazine/Dronedarone Fixed-Dose Combination
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Structure
Formula
C24H33N3O4
Molecular Weight
427.545
Canonical SMILES
COc1ccccc1OCC(O)CN1CCN(CC(=O)Nc2c(C)cccc2C)CC1
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InChI
InChI=1S/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)
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InChIKey
XKLMZUWKNUAPSZ-UHFFFAOYSA-N
CAS
142387-99-3
95635-55-5
Physicochemical Property
logP
2.30804
Rotatable Bonds
9
Heavy Atom Count
31
Polar Areas
74.27
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 56959
SID: 12013498
ChEMBL ID
CHEMBL1404
DrugBank ID
DB00243
Clinical Information about the Compound
Drug 1 ( Ranolazine )
Drug Name Ranolazine
Company CV Therapeutics
Indication
Chronic/stable angina
Approved
Paroxysmal atrial fibrillation
Phase 2
Target(s)
Plasminogen (PLG)
 Target Info 
Modulator