General Information of the Compound
Compound ID
CP0185592
Compound Name
1-[(3-naphthalen-2-yl)-(1,2,4-triazol-4-yl) ]-3-phenol
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Structure
Formula
C18H13N3O
Molecular Weight
287.322
Canonical SMILES
Oc1cccc(c1)-n1cnnc1-c1ccc2ccccc2c1
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InChI
InChI=1S/C18H13N3O/c22-17-7-3-6-16(11-17)21-12-19-20-18(21)15-9-8-13-4-1-2-5-14(13)10-15/h1-12,22H
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InChIKey
VVFHMZNOUZIYLJ-UHFFFAOYSA-N
Physicochemical Property
logP
3.7931
Rotatable Bonds
2
Heavy Atom Count
22
Polar Areas
50.94
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
22

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11666402
SID: 16770193
ChEMBL ID
CHEMBL379717
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01200, Delta-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2100 nM
   TI
   LI
   LO
   TS
Protein ID: PT00983, Kappa-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS