General Information of the Compound
Compound ID
CP0181203
Compound Name
1-[2-[4-(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-ylmethylamino)piperidin-1-yl]ethyl]-2-oxoquinoline-7-carbonitrile
    Show/Hide
Structure
Formula
C25H27N5O3
Molecular Weight
445.523
Canonical SMILES
O=c1ccc2ccc(cc2n1CCN1CCC(CC1)NCc1cc2OCCOc2cn1)C#N
    Show/Hide
InChI
InChI=1S/C25H27N5O3/c26-15-18-1-2-19-3-4-25(31)30(22(19)13-18)10-9-29-7-5-20(6-8-29)27-16-21-14-23-24(17-28-21)33-12-11-32-23/h1-4,13-14,17,20,27H,5-12,16H2
    Show/Hide
InChIKey
SEYRFRYGJGGXBD-UHFFFAOYSA-N
Physicochemical Property
logP
2.29358
Rotatable Bonds
6
Heavy Atom Count
33
Polar Areas
92.41
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 15983304
SID: 24262331
ChEMBL ID
CHEMBL2165062