General Information of the Compound
Compound ID
CP0162405
Compound Name
(4-Hydroxy-3-iodo-5-methoxy-phenyl)-acetic acid (2R,3S,3aR,5R,5aR,8bR,11aR)-3b-benzyloxy-11a-hydroxy-5a-isopropenyl-2,4-dimethyl-1-oxo-1,3a,3b,4,5,5a,8a,8b,11,11a-decahydro-6,8-dioxa-indeno[5,4-e]azulen-10-ylmethyl ester
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Structure
Formula
C37H41IO9
Molecular Weight
756.63
Canonical SMILES
COc1cc(CC(=O)OCC2=C[C@H]3[C@H]4OCO[C@]4(C[C@@H](C)[C@]3(OCc3ccccc3)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)cc(I)c1O
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InChI
InChI=1S/C37H41IO9/c1-21(2)36-16-23(4)37(46-19-24-9-7-6-8-10-24)27(34(36)45-20-47-36)12-26(17-35(42)30(37)11-22(3)33(35)41)18-44-31(39)15-25-13-28(38)32(40)29(14-25)43-5/h6-14,23,27,30,34,40,42H,1,15-20H2,2-5H3/t23-,27+,30-,34-,35-,36-,37-/m1/s1
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InChIKey
ABSOHSGIQKEXPA-XAEYSEGOSA-N
Physicochemical Property
logP
5.5969
Rotatable Bonds
9
Heavy Atom Count
47
Polar Areas
120.75
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
47

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44386779
ChEMBL ID
CHEMBL408581
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02183, Transient receptor potential cation channel subfamily V member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 0.4 nM
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