General Information of the Compound
Compound ID
CP0150343
Compound Name
(4,6-dimethylpyrimidin-2-ylamino)(2-(5-fluoro-1H-indol-3-yl)ethylamino)methaniminium
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Structure
Formula
C17H19FN6
Molecular Weight
326.379
Canonical SMILES
Cc1cc(C)nc(NC(N)=NCCc2c[nH]c3ccc(F)cc23)n1
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InChI
InChI=1S/C17H19FN6/c1-10-7-11(2)23-17(22-10)24-16(19)20-6-5-12-9-21-15-4-3-13(18)8-14(12)15/h3-4,7-9,21H,5-6H2,1-2H3,(H3,19,20,22,23,24)
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InChIKey
GBIINFPBTMFBRG-UHFFFAOYSA-N
Physicochemical Property
logP
2.68314
Rotatable Bonds
4
Heavy Atom Count
24
Polar Areas
91.98
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 16646020
SID: 99311240
ChEMBL ID
CHEMBL1094986
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Activity = 200 nM