General Information of the Compound
Compound ID
CP0146740
Compound Name
US8742106, 1.18
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Structure
Formula
C24H21F3N4O2
Molecular Weight
454.452
Canonical SMILES
CC(NC(=O)COc1cc(c2c(nn(C)c2n1)-c1ccccc1)C(F)(F)F)c1ccccc1
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InChI
InChI=1S/C24H21F3N4O2/c1-15(16-9-5-3-6-10-16)28-19(32)14-33-20-13-18(24(25,26)27)21-22(17-11-7-4-8-12-17)30-31(2)23(21)29-20/h3-13,15H,14H2,1-2H3,(H,28,32)
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InChIKey
OFEXDHUBLMOHCY-UHFFFAOYSA-N
Physicochemical Property
logP
4.9103
Rotatable Bonds
6
Heavy Atom Count
33
Polar Areas
69.04
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 50799599
ChEMBL ID
CHEMBL3634006