General Information of the Compound
Compound ID
CP0137965
Compound Name
[1-(2-fluoro-5-hydroxybenzoyl)piperidin-4-yl]-(4-phenylsulfanylphenyl)methanone
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Formula
C25H22FNO3S
Molecular Weight
435.52
Canonical SMILES
Oc1ccc(F)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Sc2ccccc2)cc1
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InChI
InChI=1S/C25H22FNO3S/c26-23-11-8-19(28)16-22(23)25(30)27-14-12-18(13-15-27)24(29)17-6-9-21(10-7-17)31-20-4-2-1-3-5-20/h1-11,16,18,28H,12-15H2
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InChIKey
SYKQOVVZSRWKHB-UHFFFAOYSA-N
Physicochemical Property
logP
5.4176
Rotatable Bonds
5
Heavy Atom Count
31
Polar Areas
57.61
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4747585